doi: https://doi.org/10.1101/847855 Link: https://www.biorxiv.org/content/biorxiv/early/2019/11/19/847855.full.pdf Advancement of high throughput sequencing technologies have enabled researchers to identify or screen cancer causing structural variants. Long-read, single molecule sequencing technologies from Pacific Biosciences (PacBio) and Oxford Nanopore Technologies (ONT) have been shown as most reliable…
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We provide data analysis services for all Next Generaton Sequencing (NGS) platform that include Illumina, Ion Torrent and Pacbio.
Identify diffrentially expressed genes, generate transcriptome assembly and study alternative spilicing events across samples with our suite of bioinformatics pipelines.
Generate high quality genome assembly ready for annotaion. We expertise in short read, long read or hybrid as per project demands.
Explore the diversity and fucntions of microbes present in samples. Robust pipelines for shotgun metagenomics assembly, identify genes and pathways in environmental or clinical samples.
Use our robust pipelines to identify structural variants – INDELS, CNVs and STRs using short reads or long reads data for your genomic studies.
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We offer quick and high quality next-generation sequencing data analysis and bioinformatics services. Our dedicated team of experts work with you at every phase of project to deliver optimal results for your research and clinical studies. A team of bioinformaticians and computer scientists are constantly working to build advance data analysis pipeline to deliver best sequencing and bioinformatics data analysis results to you.
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Next Generation Sequencing reveals transcriptional analysis of Masson Pine (Pinus massoniana) under High CO2 Stress
Link: https://www.mdpi.com/2073-4425/10/10/804/htm Citation: Genes 2019, 10(10), 804; https://doi.org/10.3390/genes10100804 Masson pine (Pinus massoniana) is a conifer species distributed in 17 provinces, autonomous regions and municipalities located south of the Qinling Mountains in China. It thrives in a warm and humid climate, growing in arid,…
Citation: 16 September 2019 / Accepted: 27 September 2019 / Published: 11 October 2019 Link: https://www.mdpi.com/2304-8158/8/10/480/htm In recent years advancement in high throughput next generation sequencing has enabled researchers to detect the entire bacterial diversity/biodiversity spectra and foodborne pathogens in…
First Human chromosome Y sequence was published nearly two decades ago, yet the full chr Y sequence is not competently resolved due to high repeat content. Chr Y is a highly complex and posses great challenges in generating a high…
The Pomegranate (Punica granatum L.) draft de novo genome assembly explores genetic divergence between soft and hard seeded cultivars
In this study, researcher’s generated a high‐quality and long‐range contiguity chromosome‐scale de novo genome assembly of the soft‐seeded pomegranate cultivar ‘Tunisia’ with the help of pacbio long reads sequencing and high‐throughput chromosome conformation capture techniques. Re-sequencing of 26 pomegranate varieties…
De novo Transcriptome Assembly and Differential Gene Expression analysis Identify Drought Resistant genes in Cynanchum thesioides (Xerophytic shrubs)
RNA sequencing (RNA Seq) is revolutionizing the study of the transcriptomes. Highly sensitive and accurate tool for measuring expression across the transcriptome, RNA Seq provides researchers with visibility into previously undetected changes occurring in disease states, in response to therapeutics,…
16s rRNA metagenomics and biodiversity analysis of melt water soil reveals a diverse community composition across soil to sediments.
Lakes of melt water in the Artic have become one of the transforming landscapes due to global warming. A recent study compares structure of microbiomes and their functions in lake sediments under melted water and soils in bank slopes 16S…
Differential Gene Expression Analysis of RNA Seq and Microarray Data highlights role of Hfq gene in expression regulation and parthenogenesis
Hfq is a conserved RNA-binding protein with multiple regulatory roles within the prokaryotic cell. One of the key roles is to promote stable duplex formation between small RNAs and mRNAs and thus Hfq deletion mutants have pleiotropic phenotypes. This study represents first…
16s rRNA profiling of Inflammatory Bowel Syndrome reveals possible role of microbiota disturbance and fecal microbiota as a remedy
IBS (Irritable Bowel Syndrome) affects between 25 and 45 million Americans. Most of them are women. People are most likely to get the condition in their late teens to early 40s. It is hypothesized that disturbance in gut microbiota may…
RNA Seq Identifies signatures in Biliary Atresia pediatric samples missed by traditional histopathology or serum liver malfunction markers
Transcriptome analysis by next-generation sequencing (RNA-seq) allows investigation of a transcriptome at unsurpassed resolution. One major benefit is that RNA-seq analysis is independent of a priori knowledge on the sequence under investigation, thereby also allowing analysis of poorly characterized Plasmodium species. Several RNA Seq pipelines are developed for…